Related Experiment Video
Updated: Jun 20, 2026
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Diffusion-weighted imaging and ADC mapping of head-and-neck paragangliomas: initial experience
René Aschenbach1, Steffen Basche, Thomas Josef Vogl
1Department of Diagnostic and Interventional Radiology and Neuroradiology, HELIOS Klinikum Erfurt GmbH, Erfurt, Germany. rene.aschenbach@helios-kliniken.de
Background:
Paragangliomas are rare, hypervascularized benign tumors. In some cases a clear differentiation of paragangliomas and other entities is impossible.
Patients And Methods:
The authors evaluated ten patients with skull base lesions (paraganglioma n = 7, meningioma n = 1, giant cell tumor n = 1, and neurinoma n = 1) in addition to conventional magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), and calculation of apparent diffusion coefficient (ADC).
Results:
Mean ADC values +/- standard deviation of the paragangliomas were 1.304 +/- 0.257 x 10(-3) mm(2)/s and differed from ADC values of the other jugular fossa tumors with 0.743 +/- 0.108 x 10(-3) mm(2)/s and measurement derived from the cerebellum with 0.802 +/- 0.075 x 10(-3) mm(2)/s.
Conclusion:
Due to the difference of ADC values, the authors propose that DWI and ADC mapping could be a promising tool in the diagnostic work-up of paragangliomas.
