[Structural and functional analysis of araN gene in the Yersinia pestis strains of various origin]

Structural and functional analysis of the araN gene involved in regulation of expression of diagnostically significant symptom (arabinose fermentation) was performed in the Yersinia pestis microorganism. Lack of arabinose fermentation in the Altai substrain, Hissar substrain, and Talas strains was shown to be due to solitary nucleotide insert into the araN gene. The insert is in the position 763 bp. The strains of the main, Caucasian, and Ulege substrains do not contain this mutation of the araN gene. The absence of the mutation correlates with ability to ferment arabinose.