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The heart of patients with aortic aneurysms: evidence from cardiac computed tomography
Paul Stolzmann1, Catherine Phan, Lotus Desbiolles
1Institute of Diagnostic Radiology, University Hospital Zurich, Zurich, Switzerland. paul.stolzmann@usz.ch
Insights
Cardiac CT effectively assesses coronary artery disease and calcium burden in abdominal aortic aneurysm patients, offering insights beyond traditional risk scores.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Aortic Aneurysm Research
Background:
- Abdominal aortic aneurysm (AAA) patients often have coexisting coronary artery disease (CAD).
- Assessing cardiovascular risk in AAA patients is crucial for management.
- Traditional risk factors may not fully capture CAD prevalence in this population.
Purpose of the Study:
- To evaluate coronary calcium burden and CAD prevalence in AAA patients.
- To correlate these findings with cardiovascular risk factors.
- To assess left ventricular (LV) function using cardiac computed tomography (CT).
Main Methods:
- Sixty consecutive AAA patients underwent dual-source CT for calcium scoring and coronary angiography before AAA repair.
- Framingham risk score (FRS) was calculated for all patients.
- Cardiac CT assessed coronary calcium, stenoses, and LV function (ejection fraction).
Main Results:
- 33% of patients had intermediate to high cardiovascular risk based on FRS.
- Median Agatston score (AS) was 393; no significant correlation between AS and FRS.
- 55% of patients had significant coronary stenoses; 8% showed reduced LV function.
Conclusions:
- Cardiac CT is feasible for assessing coronary calcium, CAD, and LV function in AAA patients.
- Coronary calcium burden and stenoses detected by CT provide information beyond traditional risk factors.
- CT assessment aids in comprehensive cardiovascular risk evaluation for AAA patients.
Abstract:
To determine in patients with abdominal aortic aneurysm (AAA) the coronary calcium burden and prevalence of coronary artery disease (CAD) in relation to cardiovascular risk factors, and to assess the left ventricular (LV) function using cardiac computed tomography (CT). Sixty consecutive patients (six females; 72.2+/-9.0 years) with AAA underwent dual-source CT calcium scoring and coronary angiography prior to AAA repair. In the 60 patients, the Framingham risk score (FRS) ranged from 5-43%. Twenty patients (33%) were at low, 16 (27%) at intermediate, and 24 (40%) at high risk for cardiovascular disease. The median Agatston score (AS) was 393 (0-3538). No significant correlation was found between AS and FRS (P=0.76). 846/851 coronary segments (99%) in 57/60 patients (95%) were depicted with a diagnostic image quality. Significant stenoses were found in 132/846 segments (16%) in 33/60 patients (55%). Five patients (8%) with significant coronary artery stenosis showed reduced LV function [ejection fraction (EF)<50%]. The extent of CAD was significantly correlated with AS (r=0.43, P<0.01), whereas no correlation was found for FRS (P=0.55). Cardiac CT is feasible in patients with AAA and allows for the assessment of coronary calcium, coronary stenoses, and LV function. The calcium burden and coronary stenoses assessment with cardiac CT provides incremental information beyond traditional cardiovascular risk factors alone.
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