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Determining gastric cancer resectability by dynamic MDCT
Zilai Pan1, Huan Zhang, Chao Yan
1Department of Radiology, Ruijin Hospital affiliated to Jiaotong University, 197 Ruijin Er Road, Shanghai 200025, China.
European Radiology
|August 27, 2009
Summary
Dynamic enhanced multi-detector row CT (MDCT) accurately stages gastric cancer and predicts tumor resectability before surgery. This imaging technique aids in preoperative planning for gastric cancer patients.
Area of Science:
- Radiology
- Oncology
- Surgical Oncology
Background:
- Multi-detector row CT (MDCT) is a standard imaging modality for cancer detection and staging.
- Accurate preoperative assessment of gastric cancer resectability is crucial for treatment planning.
Purpose of the Study:
- To evaluate the accuracy of dynamic MDCT in determining the resectability of gastric cancer.
- To assess the utility of MDCT for TNM staging of gastric cancer.
Main Methods:
- A total of 350 patients with biopsy-proven gastric cancer underwent dynamic enhanced MDCT before surgery.
- MDCT findings for TNM staging and resectability were correlated with surgical and pathological outcomes.
Main Results:
- MDCT demonstrated high accuracy for gastric cancer staging, particularly for T1 tumors (94.3%) and N2 lymph node involvement (87.3%).
- The overall accuracy of MDCT in predicting resectability was 87.4%, with a sensitivity of 89.7% and specificity of 76.7%.
- High sensitivity was observed for detecting peritoneal seeding (90.0%) and liver metastases (80.0%).
Conclusions:
- Dynamic enhanced MDCT is a valuable tool for preoperative TNM staging of gastric cancer.
- MDCT effectively predicts tumor resectability, aiding in surgical planning and patient management.