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Updated: Jun 20, 2026
Disentangling Glycan-Protein Interactions: Nuclear Magnetic Resonance (NMR) to the Rescue
Published on: May 17, 2024
Gold nanoparticle based plasmon resonance light-scattering method as a new approach for glycogen-biomacromolecule
Minghui Xiang1, Xiao Xu, Feng Liu
1Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Analytical Chemistry, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
Abstract:
A model was developed for the interactions between glycogen and biomacromolecules by gold nanoparticle plasmon resonance light-scattering method. The interactions between glycogen and biomacromolecules can alter the aggregation status of gold nanoparticles, which produced intensity changes in plasmon resonance light-scattering. This is a sensitive method to study the interactions between glycogen and biomacromolecules from nano- to micromolar level. And it is also a simple method that measurement can be carried out with a common fluorospectrometer using label-free gold nanoparticles as the transducer.
