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A fluorescence "turn-on" ensemble for acetylcholinesterase activity assay and inhibitor screening
Lihua Peng1, Guanxin Zhang, Deqing Zhang
1Beijing National Laboratory for Molecular Sciences, Organic Solids Laboratory, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Organic Letters
|August 28, 2009
Abstract:
By making use of the aggregation-induced emission feature of compound 1 and the cascade reactions among acetylthiocholine iodide (ATC), AChE, and compound 2, a new fluorescence "turn-on" method is developed for AChE assay and inhibitor-screening.
