Related Experiment Video
Updated: Jun 20, 2026

07:24
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Endophthalmitis caused by Vibrio alginolyticus
Xiao Chun Li1, Zhen Yang Xiang, Xiao Ming Xu
1Department of Ophthalmology, Taizhou Hospital of Zhejiang Province, Zhejiang, China.
Journal of Clinical Microbiology
|August 28, 2009
Summary
Vibrio alginolyticus, a marine bacterium, rarely causes eye infections. This case highlights the risk of endophthalmitis from V. alginolyticus after ocular trauma.
Area of Science:
- Ophthalmology
- Microbiology
Background:
- Vibrio alginolyticus is a Gram-negative bacillus commonly found in marine environments.
- Ocular infections caused by V. alginolyticus are exceptionally rare.
Observation:
- A rare case of endophthalmitis was observed.
- The infection was caused by Vibrio alginolyticus following an ocular injury.
Findings:
- Vibrio alginolyticus can lead to severe intraocular infections like endophthalmitis.
- Prompt recognition and treatment are crucial for managing V. alginolyticus endophthalmitis.
Implications:
- This case underscores the importance of considering V. alginolyticus in the differential diagnosis of endophthalmitis, especially after marine-associated or traumatic eye injuries.
- Further research may elucidate the specific mechanisms and risk factors for V. alginolyticus ocular infections.
Related Concept Videos
Bacterial Meningitis II: Pathophysiology
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Bacterial Meningitis
Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Cholera
Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Microbiome of the Eye
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
