Reversible intraventricular conduction defect in aconitine poisoning

Area of Science:

• Cardiology
• Integrative Medicine
• Pharmacology

Background:

• Chinese medicine, including the herb aconite (processed Fuzi), is widely used in Hong Kong.
• Aconite has a narrow therapeutic index, increasing the risk of toxicity.
• Cardiac arrhythmias, such as ventricular arrhythmias, are known potential toxicities.

Observation:

• A 57-year-old woman presented with cardiac issues.
• Her condition was linked to the consumption of processed Fuzi.
• The patient experienced a reversible intraventricular conduction defect.

Findings:

• Processed Fuzi can induce serious cardiac adverse events.
• Intraventricular conduction defects are a potential manifestation of aconite toxicity.
• The cardiac abnormality in this case was reversible upon cessation of the herb.

Implications:

• Clinicians should be aware of potential cardiac toxicities associated with Chinese herbal medicine like processed Fuzi.
• Prompt recognition and management are crucial for reversible conditions.
• Further research into the safe use and monitoring of potent herbal ingredients is warranted.