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Radiographic repair in three Japanese patients with rheumatoid arthritis treated with bucillamine
Yuki Nanke1, Masako Iwatani, Tsuyoshi Kobashigawa
1Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo, 162-0054, Japan. ynn@ior.twmu.ac.jp
Modern Rheumatology
|August 28, 2009
Abstract:
Bucillamine (Bc) is a cysteine derivative with two SH groups, and a homolog of D-penicillamine, a disease-modifying antirheumatic drug (DMARD) widely used in Japan. However, it remains unclear whether Bc repairs bone erosion in patients with RA. Here, we treated three RA patients with Bc who subsequently showed radiographic repair of erosions and cysts.