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Related Concept Videos

Three Developmental Domains01:29

Three Developmental Domains

Human development is typically examined across three main domains: physical, cognitive, and socio-emotional. These domains represent the significant areas of change and continuity throughout the lifespan, from infancy to late adulthood.
Physical Development
Physical processes, also known as maturation, encompass the biological changes that occur across an individual's life. These changes begin with genetic inheritance and continue through various stages, including growth in height and weight,...
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Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

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Introduction to Developmental Psychology

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Emerging Adulthood

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Related Experiment Video

Updated: Jun 20, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

[From preterm birth to adulthood].

Kaija Mikkola1, Viena Tommiska, Petteri Hovi

  • 1HUS:n lasten ja nuorten sairaala, neonatologian yksikkö, PL 800, 00029 HUS.

Duodecim; Laaketieteellinen Aikakauskirja
|August 29, 2009
PubMed
Summary

Outcomes for low birthweight infants have improved, but many still face neurological impairments and cardiovascular risks. Despite challenges, most achieve normal adult lives with fewer high-risk behaviors.

Area of Science:

  • Neonatal care
  • Developmental pediatrics
  • Perinatal epidemiology

Context:

  • Significant advancements in neonatal intensive care have improved survival rates for low birthweight infants.
  • Despite improved outcomes, a substantial proportion of extremely low birthweight infants (birthweight < 1000 g) experience significant neurological impairments.
  • Long-term neurodevelopmental and health trajectories for these infants require continued investigation.

Purpose:

  • To assess the neurological prognosis and long-term health outcomes for infants born with low birthweight.
  • To identify persistent challenges and risk factors associated with prematurity.
  • To understand the adult life course of individuals born with very low birthweight.

Summary:

  • Mortality rates for low birthweight infants have declined, with notable improvements in neurological prognosis over recent decades.

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Preterm EEG: A Multimodal Neurophysiological Protocol

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A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

Published on: January 7, 2018

Related Experiment Videos

Last Updated: Jun 20, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Preterm EEG: A Multimodal Neurophysiological Protocol
19:32

Preterm EEG: A Multimodal Neurophysiological Protocol

Published on: February 18, 2012

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis
06:19

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

Published on: January 7, 2018

  • Approximately one-fifth of infants born weighing less than 1000 grams exhibit major neurological impairments by preschool age.
  • While most low birthweight survivors lead relatively normal adult lives, they face increased cardiovascular disease risk factors compared to full-term infants, yet display less high-risk behavior.

    • Impact:

    • Highlights the need for ongoing neurodevelopmental surveillance and targeted interventions for extremely low birthweight survivors.
    • Informs clinical practice regarding the long-term management of cardiovascular risk in this vulnerable population.
    • Provides insights into the complex interplay between prematurity, neurodevelopment, and adult health behaviors.