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Mechanical ventilation of the neonate: should we target volume or pressure?
1Division of Neonatal-Perinatal Medicine, Department of Pediatrics, F5790, Mott Children's Hospital, University of Michigan Health System, 1500 E Medical Center Drive, Ann Arbor MI 48109-0254, USA. smdonnmd@med.umich.edu
Abstract:
For more than 40 years conventional mechanical ventilation has been used for the treatment of neonatal respiratory failure. Until relatively recently, this was accomplished with time-cycled pressure-limited ventilation, using intermittent mandatory ventilation. Earlier attempts at volume-targeted ventilation were largely ineffective because of technological limitations. The advent of microprocessor-based devices gives the clinician an option to choose either target variable to treat neonatal patients. This paper reviews the principles of each and the accumulated evidence.
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