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Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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Intratracheal Inoculation of Fischer 344 Rats with Francisella tularensis
06:09

Intratracheal Inoculation of Fischer 344 Rats with Francisella tularensis

Published on: September 30, 2017

Tularemia.

Janet E Foley1, Nathan C Nieto

  • 1Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. jefoley@ucdavis.edu

Veterinary Microbiology
|August 29, 2009
PubMed
Summary
This summary is machine-generated.

Tularemia is a severe bacterial disease caused by Francisella tularensis, affecting humans and animals globally. This review covers its microbiology, pathology, epidemiology, and ecological factors.

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Trichuris muris Infection: A Model of Type 2 Immunity and Inflammation in the Gut

Published on: May 24, 2011

Area of Science:

  • Microbiology
  • Pathology
  • Epidemiology
  • Ecology

Background:

  • Tularemia is a potentially fatal, multi-systemic disease caused by the bacterium Francisella tularensis.
  • It affects humans and animals across the Northern Hemisphere, transmitted via ticks, flies, water, food, and aerosols.
  • Francisella tularensis subspecies vary in pathogenicity, with F. tularensis subsp. tularensis being highly pathogenic in North America.

Purpose of the Study:

  • To provide a comprehensive overview of tularemia.
  • To discuss the microbiological, clinicopathological, epidemiological, and ecological aspects of the disease.
  • To highlight Francisella tularensis as a potential biological warfare agent.

Main Methods:

  • Review of existing literature on tularemia.
  • Synthesis of information on disease transmission and vectors.
  • Classification and discussion of Francisella tularensis subspecies.

Main Results:

  • Tularemia presents diverse clinical and pathological features.
  • Geographic distribution spans North America, Europe, and Asia.
  • Francisella tularensis is a significant public health concern due to its infectivity and potential misuse.

Conclusions:

  • Tularemia is a serious zoonotic disease with significant public health implications.
  • Understanding its multifaceted aspects is crucial for prevention and control.
  • Its classification as a select agent underscores the need for vigilance.