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Updated: Jun 20, 2026

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Published on: November 26, 2018
Genetic lesions in chronic lymphocytic leukemia: clinical implications
Emili Montserrat1, Carol Moreno
1Institute of Hematology and Oncology, Department of Hematology, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Villarroel, Barcelona, Spain. emontse@clinic.ub.es
Purpose Of Review:
To analyze recent scientific contributions correlating genetic lesions with clinical features in chronic lymphocytic leukemia (CLL).
Recent Findings:
Genetic abnormalities are increasingly important to understand not only CLL biology but also other aspects such as its epidemiology, diagnosis, prognosis, and clinical evolution.
Summary:
Genetic abnormalities provide important clues in understanding the clinical and biologic heterogeneity of CLL, assessing the individual risk of each patient with this form of leukemia and also predicting response to therapy.
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