National, state, and local area vaccination coverage among children aged 19-35 months - United States, 2008

    Insights

    In 2008, national childhood vaccination coverage for the 4:3:1:3:3:1 series was 76.1%, with notable state-level variations and lower rates among children in poverty. Maintaining high vaccination coverage is crucial for preventing disease.

    Area of Science:

    • Immunology
    • Public Health
    • Epidemiology

    Background:

    • The National Immunization Survey (NIS) tracks vaccination coverage in children aged 19-35 months across the US.
    • Healthy People 2010 set targets of 90% for individual vaccines and 80% for the 4:3:1:3:3:1 series.

    Purpose of the Study:

    • To report 2008 NIS vaccination coverage estimates for the 4:3:1:3:3:1 series, individual vaccines, pneumococcal conjugate vaccine (PCV7), hepatitis A vaccine (HepA), and hepatitis B birth dose (HepB).
    • To analyze coverage variations by state/local area, race/ethnicity, and poverty status.

    Main Methods:

    • Analysis of 2008 National Immunization Survey data for children born January 2005–June 2007.
    • Estimation of vaccination coverage rates for the 4:3:1:3:3:1 series and specific vaccines.

    Main Results:

    • Overall 4:3:1:3:3:1 series coverage was 76.1% in 2008, a slight decrease from 77.4% in 2007.
    • Coverage for diphtheria, tetanus, and acellular pertussis (DTaP) with >=4 doses fell below 90%.
    • Haemophilus influenzae type b (Hib) coverage decreased, potentially due to vaccine shortages and revised recommendations.
    • Significant state-level disparities in coverage were observed.
    • Coverage varied little by race/ethnicity but was lower for children living below the poverty level.

    Conclusions:

    • Sustaining high vaccination coverage remains essential for protecting children against vaccine-preventable diseases.
    • Addressing disparities in vaccination coverage across states and income groups is a public health priority.

    Related Concept Videos

    Vaccinations01:51

    Vaccinations

    Overview
    Smallpox01:24

    Smallpox

    Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
    Drug Dosing: Infants and Children01:29

    Drug Dosing: Infants and Children

    Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
    Vaccines01:21

    Vaccines

    Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...
    Methods Of Healthcare Delivery System01:26

    Methods Of Healthcare Delivery System

    At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
    Managed Care System:
    The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is limited...
    Poliomyelitis01:17

    Poliomyelitis

    Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...