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Updated: Jun 20, 2026

Targeted RNA Sequencing Assay to Characterize Gene Expression and Genomic Alterations
Published on: August 4, 2016
Applications of new sequencing technologies for transcriptome analysis
Olena Morozova1, Martin Hirst, Marco A Marra
1BC Cancer Agency, Genome Sciences Center, Vancouver, BC V5Z 4S6, Canada. omorozova@bcgsc.ca
Abstract:
Transcriptome analysis has been a key area of biological inquiry for decades. Over the years, research in the field has progressed from candidate gene-based detection of RNAs using Northern blotting to high-throughput expression profiling driven by the advent of microarrays. Next-generation sequencing technologies have revolutionized transcriptomics by providing opportunities for multidimensional examinations of cellular transcriptomes in which high-throughput expression data are obtained at a single-base resolution.
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