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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
iPS Cell Differentiation01:22

iPS Cell Differentiation

The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.

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Related Experiment Video

Updated: Jun 20, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

[An update on scalp psoriasis].

J Sola-Ortigosa1, M Sánchez-Regaña, P Umbert-Millet

  • 1Unidad de Psoriasis y Fototerapia, Unidad Docente de la Universidad de Barcelona. Barcelona. España. 38725jso@comb.es

Actas Dermo-Sifiliograficas
|September 1, 2009
PubMed
Summary
This summary is machine-generated.

Scalp psoriasis affects up to 80% of patients, causing significant psychological distress. Combination therapy with potent corticosteroids and vitamin D3 analogues offers a safe and effective treatment with rapid results and long-term safety.

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Measuring Psoriasis Severity at Home
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Last Updated: Jun 20, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Area of Science:

  • Dermatology
  • Clinical Medicine
  • Pharmacology

Context:

  • Scalp psoriasis affects 50-80% of psoriasis patients.
  • Clinical presentation varies from mild to severe.
  • Significant psychological impact is common.

Purpose:

  • To review effective treatments for scalp psoriasis.
  • To identify ideal treatment characteristics: efficacy, convenient application, long-term safety.
  • To highlight combination therapy with corticosteroids and vitamin D3 analogues.

Summary:

  • Numerous treatments exist, including phototherapy, keratolytics, and topical agents.
  • Ideal scalp psoriasis treatments should be effective, easy to apply (lotion, foam, emulsion), require infrequent application, and possess long-term safety.
  • Potent corticosteroids combined with vitamin D3 analogues demonstrate fast action and established long-term safety.

Impact:

  • Provides guidance for tailoring scalp psoriasis treatment to individual needs.
  • Emphasizes the importance of balancing efficacy with safety and convenience.
  • Supports the use of combination therapy for improved patient outcomes and quality of life.