Related Experiment Video
Updated: Jun 20, 2026

Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice
Published on: June 29, 2022
The atrioventricular interval during pre-excited tachycardia: a simple way to distinguish between decrementally or
Eduardo Back Sternick1, Yash Lokhandwala, Carl Timmermans
1Arrhythmia and Electrophysiology Unit, Biocor Instituto, Nova Lima, Brazil. eduardosternick@terra.com.br
Background:
Recognition of the presence and role of decremental fibers during wide QRS tachycardia requires carefully executed intracardiac studies.
Objective:
This study sought to determine the value of the atrioventricular (AV) conduction time during pre-excited tachycardia to differentiate a fast from a decrementally conducting accessory pathway (AP).
Methods:
Fifty-one patients with 56 pre-excited tachycardias were included in the study: Group I: 27 patients with 31 antidromic tachycardia (ADT) using an atriofascicular pathway, Group II: 2 patients with pre-excited tachycardia due to bystander AV conduction, Group III: 3 patients with ADT and a short AV Mahaim fiber, and Group IV: 19 patients with 21 ADT using a fast conducting right-sided AP. The AV interval was measured in the His bundle electrogram and related to the tachycardia cycle length (TCL) by making an AV/TCL index.
Results:
An AV interval > or = 150 ms during pre-excited tachycardia yielded a 91% sensitivity, 90% specificity, positive predictive value of 94%, and negative predictive value of 83% for AV conduction over a decrementally conducting pathway, whereas a > or =0.55 AV/TCL index yielded a sensitivity of 89%, specificity of 100%, positive predictive value of 100%, and negative predictive value of 84%. In 3 of 4 patients with Mahaim fibers and a <0.55 AV/TCL index, a prolonged ventriculoatrial (VA) conduction time was found.
Conclusions:
An AV interval > or =150 ms during pre-excited tachycardia is a fast and reliable method for detecting a decrementally conducting AP. Correcting the AV interval by the tachycardia cycle length improved specificity and positive predictive accuracy.
Related Concept Videos
Dysrhythmias III: Characteristics of Dysrhythmias
Dysrhythmias IV: Characteristics of Bradyarrhythmias
Conduction System of the Heart
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
Conduction System of the Heart
This system relies on the unique properties of nodal and Purkinje cells:...
Electrophysiology of Normal Cardiac Rhythm
Mechanism of Cardiac Arrhythmias

