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Updated: Jun 20, 2026

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
Published on: September 25, 2019
Distinct location of subcortical silent infarcts compared with symptomatic lacunar infarcts
1Department of Neurology, Dankook University Hospital, Cheonan, Chungnam 330-715, South Korea. ymsong@medimail.co.kr
Objective:
To determine whether the location of subcortical silent infarcts differs from that of symptomatic lacunar infarcts.
Methods:
32 silent infarcts and 59 acute lacunar infarcts located in the corona radiata were examined. The relative anterior-to-posterior locations of the silent infarcts in the corona radiata were compared with those of the symptomatic lacunes on T2-weighed MR imaging.
Results:
The locations of the silent infarcts differed from those of the symptomatic lacunar lesions in the corona radiata (p<0.001). Silent infarcts were distributed principally in the anterior half of the corona radiata, whereas most of the symptomatic lacunes were located in the posterior half of the corona radiata.
Conclusion:
The asymptomatic nature of subcortical silent infarcts may be attributable to their location in ineloquent portions of brain structures.

