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Angiosarcoma of skull base in a 1-year-old child--a case report
Gayathri Mandya Renukaswamy1, Simone J Boardman, Neil J Sebire
1Otolaryngology Department, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom.
Abstract:
Angiosarcoma is a rare tumour of endothelial cell origin whilst malignant skull base tumours are highly unusual in paediatric patients. This case reports an angiosarcoma involving the clivus and basi-sphenoid region of the skull base, in a 1-year-old boy. This tumour is extremely rare in childhood, particularly in this site. The histological features were consistent with a high-grade haemangioendothelioma, categorised as an angiosarcoma. The characteristics of this rare malignancy and the challenges in its management are discussed. This is the youngest reported patient, to our knowledge, with an angiosarcoma of the skull base.