Related Experiment Video
Updated: Jun 20, 2026

10:20
Automation of a Positron-emission Tomography (PET) Radiotracer Synthesis Protocol for Clinical Production
Published on: October 26, 2018
Fully automated synthesis and initial PET evaluation of [11C]PBR28
Min Wang1, Karmen K Yoder, Mingzhang Gao
1Department of Radiology, Indiana University School of Medicine, 950 West Walnut Street, Room 427, Indianapolis, IN 46202, USA.
Bioorganic & Medicinal Chemistry Letters
|September 1, 2009
Abstract
None:
Fully automated synthesis and initial PET evaluation of a TSPO radioligand, [11C]PBR28 (N-(2-[11C]methoxybenzyl)-N-(4-phenoxypyridin-3-yl)acetamide), are reported. These results facilitate the potential preclinical and clinical PET studies of [11C]PBR28 in animals and humans.
![Automated Radiochemical Synthesis of [18F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F55537.jpg&w=3840&q=50)
![Technical Aspect of the Automated Synthesis and Real-Time Kinetic Evaluation of [11C]SNAP-7941](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59557.jpg&w=3840&q=50)