Related Experiment Video
Updated: Jun 20, 2026

09:49
Routine Screening Method for Microparticles in Platelet Transfusions
Published on: January 31, 2018
Platelet utilization in the developing world: strategies to optimize platelet transfusion practices.
Anupam Verma1, Prashant Agarwal
1Transfusion Medicine, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India. aver@sgpgi.ac.in
Summary
Developing countries face critical blood shortages, particularly for platelets, due to underdeveloped transfusion services. Implementing best practices is crucial for optimizing the use of these scarce and expensive blood components.
Area of Science:
- Transfusion Medicine
- Hematology
- Public Health
Background:
- Significant shortages of blood and blood components, especially platelets, persist globally, particularly in developing nations.
- Underdeveloped healthcare systems and blood transfusion services exacerbate the demand-supply gap for essential blood products.
- Limited comprehensive data on platelet utilization in developing countries hinders the advancement of blood component therapy.
Purpose of the Study:
- To highlight the challenges and variations in platelet transfusion practices in developing countries.
- To emphasize the need for standardized and optimal utilization of scarce platelet resources.
- To propose interventions for improving platelet utilization in resource-limited settings.
Main Methods:
- Review of existing literature and data on platelet transfusion practices in developing countries.
- Analysis of factors contributing to heterogeneity in transfusion protocols.
- Identification of key areas for intervention and best practice implementation.
Main Results:
- Considerable heterogeneity exists in platelet transfusion practices within and between developing countries.
- Factors such as individual preferences, lack of standardized policies, and availability issues contribute to practice variations.
- Developed nations are advancing towards platelet substitutes, contrasting with the challenges in developing regions.
Conclusions:
- There is an urgent need to implement evidence-based best practices for platelet transfusion in developing countries.
- Standardization of transfusion policies and addressing availability issues are critical for optimizing platelet use.
- Improving platelet utilization is essential given their scarcity and high cost in resource-limited settings.
More Related Videos
Related Concept Videos
Structure and Function of Platelets
The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000 platelets, with...
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000 platelets, with...
Blood Transfusion and Agglutination
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...

