Related Experiment Video
Updated: Jun 20, 2026

Antagonistic Effect of Jiawei Shengjiang San on a Rat Model of Diabetic Nephropathy: Related to EGFR/MAPK3/1 Signaling Pathway
Published on: May 10, 2024
The jasmonate pathway: the ligand, the receptor and the core signalling module
Sandra Fonseca1, Jose M Chico, Roberto Solano
1Departamento de Genética Molecular de Plantas, Centro Nacional de Biotecnología-CSIC, Campus Universidad Autónoma, 28049 Madrid, Spain.
Abstract:
Jasmonates regulate specific developmental processes and plant adaptation to environment by controlling responses to external biotic or abiotic stimuli. The core events of jasmonate signalling are now defined. After hormone perception by SCF(COI1), JAZ (JAsmonate ZIM domain) repressors are targeted for proteasome degradation, releasing MYC2 and de-repressing transcriptional activation. JAZs are homomeric and heteromeric proteins and have been instrumental in recent advances in the field, such as the identification of COI1 as a critical component of the jasmonate receptor and the discovery of the bioactive jasmonate in Arabidopsis, (+)-7-iso-JA-Ile. Small changes in jasmonate structure result in hormone inactivation and might be the key to switching-off signalling for specific responses to stimulus and for long-distance signalling events.
More Related Videos
08:54Imaging Spatial Reorganization of a MAPK Signaling Pathway Using the Tobacco Transient Expression System
Published on: March 20, 2016
07:55Luciferase Complementation Imaging Assay in Nicotiana benthamiana Leaves for Transiently Determining Protein-protein Interaction Dynamics
Published on: November 20, 2017
Related Concept Videos
The JAK-STAT Signaling Pathway
Interactions Between Signaling Pathways
Convergence and divergence, and cross-talk between signaling pathways
Two distinct signaling pathways can converge on a single functional unit, which may either be a single protein or a complex of proteins. The response is either functionally distinct or synergistic between the two pathways but different from the response...
Cell Signaling in Plants
Signal Transduction: Overview
Typically, signal transduction involves three...
Notch Signaling Pathway
The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...
Notch Signaling Pathway
The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not until 1985...