Related Experiment Video
Updated: Jun 20, 2026
10:47
High-Throughput Image-Based Quantification of Mitochondrial DNA Synthesis and Distribution
Published on: May 5, 2023
Unraveling the secrets of regulating mitochondrial DNA replication
Michele M Klingbeil1, Theresa A Shapiro
1Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA. klingbeil@microbio.umass.edu
Molecular Cell
|September 1, 2009
Abstract:
In this issue, Liu et al. (2009) report that maxicircle DNA copy number in trypanosomes is regulated by proteolysis of a helicase; the complex kinetoplast DNA system yields a clear view of how mitochondrial DNA replication can be regulated.
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