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D-aspartate oxidase activity and D-aspartate content in a mutant mouse strain lacking D-amino acid oxidase
H Nagasaki1, R Yamada, R Konno
1Department of Biochemistry, Kyoto Prefectural University of Medicine, Japan.
Experientia
|May 15, 1990
Abstract:
A mutant mouse strain ddY/DAO- lacks D-amino acid oxidase activity and accumulates free neutral D-amino acids in its tissues. In this study, D-aspartate oxidase activity and D-aspartate content in the tissues of these mutant mice were compared with those of normal mice. No significant difference was observed, indicating that the metabolism of acidic D-amino acids was unaffected in the mutant.