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Updated: Jun 20, 2026
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An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum
Published on: January 26, 2024
Breast angiosarcoma metastatic to the ovary
Frederico F Souza1, Amol Katkar, Annick D Van den Abbeele
1Department of Radiology, Dana-Farber Cancer Institute, Harvard Medical school, 44 Binney Street, Boston, MA 02215, USA.
Case Reports in Medicine
|September 1, 2009
Summary
A rare case of breast angiosarcoma metastasizing to the ovary is presented. This highlights the importance of considering unusual metastatic patterns in gynecological oncology.
Area of Science:
- Gynecologic Oncology
- Pathology
- Medical Oncology
Background:
- Ovarian masses are frequent in gynecological practice, with 5-10% being malignant.
- Primary angiosarcoma is a rare vascular tumor that can occur in the breast, typically in women aged 30-40.
- Breast angiosarcomas have a poor prognosis, characterized by high recurrence and metastasis rates.
Observation:
- This report details a unique instance of a solitary ovarian metastasis originating from a primary breast angiosarcoma.
- The metastasis was identified in a patient presenting with a common gynecological finding.
Findings:
- Angiosarcomas, though rare, can spread to distant sites like the ovary.
- Hematogenous spread is a common route for breast angiosarcoma metastasis, contrasting with typical lymphatic spread in other breast cancers.
- The case underscores the aggressive nature of angiosarcoma, with potential for late or unusual metastatic presentations.
Implications:
- This case expands the differential diagnosis for ovarian malignancies, particularly in patients with a history of angiosarcoma.
- It emphasizes the need for thorough oncological evaluation and awareness of rare metastatic patterns in gynecological diagnoses.
- Further research into the metastatic behavior of angiosarcoma may improve patient outcomes and diagnostic strategies.
