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Related Concept Videos

Gross Anatomy of the Liver01:17

Gross Anatomy of the Liver

The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is covered...
Liver Physiology01:30

Liver Physiology

The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of  70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can also...
Hepatic Portal System01:21

Hepatic Portal System

The hepatic portal system, a critical part of our circulatory framework, transports nutrient-laden, deoxygenated blood from the gastrointestinal tract and spleen to the liver. This ingenious system plays an indispensable role in maintaining our body's metabolic equilibrium.
At its core, the hepatic portal vein is the result of a confluence of the superior and inferior mesenteric veins along with the splenic vein. Each of these veins has a unique role. The superior mesenteric vein is responsible...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Liver Histology01:27

Liver Histology

The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
Liver Regeneration01:24

Liver Regeneration

The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are large...

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Related Experiment Video

Updated: Jun 20, 2026

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
10:25

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

Published on: February 19, 2019

[The liver and Europe].

J-M Pawlotsky1

  • 1Inserm U955, Centre National de Reférence des Hépatites Virales B, C et Delta, Laboratoire de Virologie, Université Paris-12, Hôpital Henri-Mondor, 94010 Créteil cedex, France. jean-michel.pawlotsky@hmn.aphp.fr

Gastroenterologie Clinique Et Biologique
|September 2, 2009
PubMed
Summary

Chronic liver disease affects 29 million in the EU but remains neglected. Public health policies and research are crucial for better management and reduced mortality from liver conditions.

Area of Science:

  • Hepatology and Public Health

Context:

  • Liver diseases represent a significant public health challenge in the European Union, affecting approximately 29 million individuals.
  • Despite progress in understanding and managing liver diseases, they have been historically neglected by political and public health decision-makers.
  • Hepatology, the study of the liver, faces challenges due to this lack of recognition.

Purpose:

  • To highlight the critical need for enhanced surveillance, data collection, and public awareness regarding liver diseases.
  • To advocate for improved treatment and management policies at both European and national levels.
  • To emphasize the importance of promoting research into the causes, prevention, and effective interventions for liver diseases.

Summary:

  • Major advancements in liver disease knowledge and management over the past 30 years contrast with their persistent neglect in public health policy.

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Human Liver Spheroids from Peripheral Blood for Liver Disease Studies
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Human Liver Spheroids from Peripheral Blood for Liver Disease Studies

Published on: January 27, 2023

Optimized and Simplified Technique for the Production and Culture of Precision-Cut Liver Slices
06:00

Optimized and Simplified Technique for the Production and Culture of Precision-Cut Liver Slices

Published on: November 22, 2024

Related Experiment Videos

Last Updated: Jun 20, 2026

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
10:25

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

Published on: February 19, 2019

Human Liver Spheroids from Peripheral Blood for Liver Disease Studies
09:51

Human Liver Spheroids from Peripheral Blood for Liver Disease Studies

Published on: January 27, 2023

Optimized and Simplified Technique for the Production and Culture of Precision-Cut Liver Slices
06:00

Optimized and Simplified Technique for the Production and Culture of Precision-Cut Liver Slices

Published on: November 22, 2024

  • The European Association for the Study of the Liver (EASL) initiated a public policy action in 2006 to elevate the recognition of liver diseases as a leading cause of morbidity and mortality.
  • Key recommendations include implementing robust data collection, public education, optimized treatment strategies, and increased research funding.

    • Impact:

    • The success of EASL's initiative is vital for the future of hepatology as a specialty.
    • Implementing proposed measures can lead to reduced incidence, prevalence, morbidity, and mortality associated with liver diseases.
    • Increased political and public recognition is essential for driving policy changes and resource allocation for liver health.