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Updated: Jun 20, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Influence of stroke subtype on quality of care in the Get With The Guidelines-Stroke Program
E E Smith1, L Liang, A Hernandez
1Calgery Stroke Program, Hotchkiss Brain Institute, University of Calgary, Department of Clinical Neurosciences, Foothills Medical Centre, 1403 29 Street NW, Calgary, AB, Canada T2N 2T9. eesmith@ucalgary.ca
Insights
Quality of care for hemorrhagic stroke (intracerebral hemorrhage and subarachnoid hemorrhage) is often lower than for ischemic stroke. However, participation in Get With The Guidelines-Stroke programs improves care quality for hemorrhagic stroke patients.
Area of Science:
- Neurology
- Public Health
- Health Services Research
Background:
- In-hospital care quality for hemorrhagic stroke subtypes, including intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH), is not well-established.
- Existing research primarily focuses on ischemic stroke (IS) care.
- Understanding care disparities is crucial for improving outcomes in all stroke types.
Purpose of the Study:
- To examine and compare the quality of hospital-based care for ICH and SAH admissions against IS and transient ischemic attack (TIA) admissions.
- To identify specific quality of care measures that are underutilized in hemorrhagic stroke.
- To assess the impact of Get With The Guidelines-Stroke (GWTG-Stroke) program participation on care quality for hemorrhagic stroke.
Main Methods:
- Analysis of 479,284 stroke and TIA admissions from 905 hospitals in the GWTG-Stroke database (April 2003–December 2007).
- Calculation of quality measure adherence proportions, excluding ineligible patients or those with contraindications.
- Use of logistic regression to compare quality measure compliance across stroke subtypes (ICH, SAH, IS, TIA), controlling for patient and hospital factors.
Main Results:
- Hemorrhagic stroke admissions (ICH, SAH) showed lower adherence to many quality care measures compared to IS/TIA, including deep venous thrombosis (DVT) prevention for ICH and smoking cessation for SAH.
- ICH patients had higher rates of rapid door-to-CT times and dysphagia screening compared to IS/TIA.
- Increased duration of GWTG-Stroke program participation correlated with significant improvements in care quality for ICH and SAH patients, notably DVT prevention and smoking cessation.
Conclusions:
- Significant underutilization of key acute care and preventive measures exists for ICH and SAH compared to IS/TIA.
- The Get With The Guidelines-Stroke program demonstrates a positive association with improved quality of care for patients with hemorrhagic stroke.
- Sustained participation in quality improvement programs is vital for enhancing hemorrhagic stroke management.
Objective:
Little is known about in-hospital care for hemorrhagic stroke. We examined quality of care in intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH) admissions in the national Get With The Guidelines-Stroke (GWTG-Stroke) database, and compared them to ischemic stroke (IS) or TIA admissions.
Methods:
Between April 1, 2003, and December 30, 2007, 905 hospitals contributed 479,284 consecutive stroke and TIA admissions. The proportions receiving each quality of care measure were calculated by dividing the total number of patients receiving the intervention by the total number of patients eligible for the intervention, excluding ineligible patients or those with contraindications to treatment. Logistic regression models were used to determine associations between measure compliance and stroke subtype, controlling for patient and hospital characteristics.
Results:
Stroke subtypes were 61.7% IS, 23.8% TIA, 11.1% ICH, and 3.5% SAH. Performance on care measures was generally lower in ICH and SAH compared to IS/TIA, including guideline-recommended measures for deep venous thrombosis (DVT) prevention (for ICH) and smoking cessation (for SAH) (multivariable-adjusted p < 0.001 for all comparisons). Exceptions were that ICH patients were more likely than IS/TIA to have door-to-CT times <25 minutes (multivariable-adjusted p < 0.001) and to undergo dysphagia screening (multivariable-adjusted p < 0.001). Time spent in the GWTG-Stroke program was associated with improvements in many measures of care for ICH and SAH patients, including DVT prevention and smoking cessation therapy (multivariable-adjusted p < 0.001).
Conclusions:
Many hospital-based acute care and prevention measures are underutilized in intracerebral hemorrhage and subarachnoid hemorrhage compared to ischemic stroke /TIA. Duration of Get With The Guidelines-Stroke participation is associated with improving quality of care for hemorrhagic stroke.
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