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Updated: Jun 20, 2026
Rose Bengal-Mediated Photodynamic Therapy to Inhibit Candida albicans
Published on: March 24, 2022
Photodynamic therapy of port-wine stains
Yuan-Gang Lu1, Jin-Jin Wu, Ya-Dong Yang
1Department of Dermatology, Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing, China. xll515@163.com
Objectives:
The purpose of this study was to observe the improvements of port-wine stains (PWSs) under photodynamic therapy (PDT) and to further evaluate the safety and efficacy of PDT in the dermatology clinic for the treatment of PWSs.
Methods:
Total of 75 PWS patients were treated with PDT. The PWS lesions were exposed to the copper vapor laser after intravenous injection of photosensitizer (Photocarcinorin, PsD-007). The lesions were photographed before each session and the therapeutic effects were evaluated by physicians based on the improvements in color, thickness and area of the photographed lesions. A follow-up visit was carried out after 2 months. The improvement rates were classified into 5 grades for quantitation of the therapeutic effects. A decision of termination or continuation of the treatment was then made according to lesion changes.
Results:
Patients with PWSs responded remarkably to PDT. The complete clinical remission rate was 57.33% and the effective rate was up to 94.67% in no more than four courses of treatment. Among the completely responded patients, 20.93% were treated with no more than two courses.
Conclusion:
PDT is safe and highly effective for the treatment of PWSs in the dermatology clinic.
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