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Updated: Jun 20, 2026

Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications
Published on: February 6, 2016
Two-photon fluorescent probes of biological Zn(II) derived from 7-hydroxyquinoline
Xiao-Yun Chen1, Jing Shi, Yi-Ming Li
1Department of Chemistry, University of Science and Technology of China, Hefei 230026, China.
Abstract:
A new fluorescent probe for monitoring Zn(2+) was synthesized based on the structure of 7-hydroxyquinoline. Compared with 8-substituted quinolines, the new probe exhibited higher selectivity for Zn(2+) over Cd(2+). Its fluorescence enhancement (14-fold) and nanomolar range sensitivity (K(d) = 0.117 nM) were favorable toward biological applications. Experiments also showed that a cell-permeable derivative of the new probe was potentially useful for two-photon imaging in living cells.
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