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Updated: Jun 20, 2026

04:29
Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
Vagus nerve stimulation
Dzenan Lulic1, Amir Ahmadian, Ali A Baaj
1Department of Neurosurgery, University of South Florida, Tampa, Florida 33612, USA.
Neurosurgical Focus
|September 3, 2009
Abstract:
Vagus nerve stimulation (VNS) is a key tool in the treatment of patients with medically refractory epilepsy. Although the mechanism of action of VNS remains poorly understood, this modality is now the most widely used nonpharmacological treatment for drug-resistant epilepsy. The goal of this work is to review the history of VNS and provide information on recent advances and applications of this technology.
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The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
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