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Inhalation Anthrax01:25

Inhalation Anthrax

Anthrax is a zoonotic disease caused by Bacillus anthracis, a Gram-positive, spore-forming bacterium. It primarily affects herbivorous animals but can be transmitted to humans through skin contact, ingestion, or inhalation of spores.Cutaneous anthrax, the most common form, typically results from direct contact with bacterial spores through skin abrasions and is generally less severe. Gastrointestinal anthrax results from eating undercooked or contaminated meat. It affects the mouth, throat, or...
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Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
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Bacterial Phylum Spirochaetes

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Feeding of Ticks on Animals for Transmission and Xenodiagnosis in Lyme Disease Research
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Published on: August 31, 2013

Anthrax in animals.

W Beyer1, P C B Turnbull

  • 1University of Hohenheim, Institute of Environmental and Animal Hygiene, 70593 Stuttgart, Germany. beyer@uni-hohenheim.de

Molecular Aspects of Medicine
|September 3, 2009
PubMed
Summary
This summary is machine-generated.

Anthrax, a zoonotic disease affecting many animals and humans, remains poorly understood regarding transmission. This study details its epidemiology, clinical signs, and pathology, aiding in disease control.

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Area of Science:

  • Veterinary Medicine
  • Infectious Diseases
  • Epidemiology

Background:

  • Anthrax is a significant zoonotic disease with a broad host range, particularly affecting herbivorous mammals.
  • The exact mechanisms of animal transmission for anthrax remain incompletely understood despite its long recognition.
  • The disease is endemic in Africa and Asia, posing risks to non-endemic regions through animal and product trade.

Purpose of the Study:

  • To provide a comprehensive overview of anthrax epidemiology, clinical signs, and pathology in animals.
  • To highlight the importance of understanding disease transmission for effective control strategies.
  • To discuss advancements in distinguishing anthrax genotypes for better epidemiological insights.

Main Methods:

  • Review and synthesis of existing knowledge on anthrax.
  • Detailed description of clinical manifestations and pathological findings in affected animals.
  • Discussion of new systems for genotypic differentiation of Bacillus anthracis.

Main Results:

  • Anthrax affects a wide array of species, with herbivorous mammals being most susceptible.
  • Geographical spread occurs through trade, with endemic regions posing ongoing risks.
  • New genotypic systems are improving the understanding of anthrax epidemiology.

Conclusions:

  • Further scientific establishment of transmission routes is crucial for anthrax control.
  • Continued vigilance is necessary in non-endemic areas to prevent outbreaks from imported cases.
  • Advancements in genotyping offer enhanced tools for epidemiological surveillance and management of anthrax.