Is complementary and alternative healthcare use associated with better outcomes in children with juvenile idiopathic

Karine Toupin-April1, Debbie Ehrmann Feldman, Maria Victoria Zunzunegui

  • 1Département de médecine sociale et préventive and Groupe de Recherche Interdisciplinaire en Santé, Université de Montréal and Centre de recherche interdisciplinaire en réadaptation, Montreal, Quebec, Canada. ktoupina@uottawa.ca

The Journal of Rheumatology
|September 3, 2009
PubMed

Insights

Complementary and alternative healthcare (CAHC) use in children with juvenile idiopathic arthritis (JIA) did not improve health outcomes. However, CAHC users showed better adherence to conventional treatments.

Area of Science:

  • Pediatric Rheumatology
  • Integrative Medicine
  • Health Services Research

Background:

  • Juvenile idiopathic arthritis (JIA) is a chronic condition requiring ongoing management.
  • Complementary and alternative healthcare (CAHC) is frequently used by patients with chronic diseases.
  • The impact of CAHC on health outcomes and treatment adherence in JIA is not well understood.

Purpose of the Study:

  • To investigate the association between CAHC use and health outcomes in children with JIA.
  • To explore the relationship between CAHC use and adherence to conventional treatments in this population.

Main Methods:

  • A one-year prospective cohort study of 182 children with JIA (mean age 10 years).
  • Regular assessment of CAHC use, health-related quality of life (HRQOL), global health, physical functioning, pain, and disease severity.
  • Evaluation of perceived adherence to prescribed medications.
  • Statistical analysis using general estimating equations to control for confounders.

Main Results:

  • CAHC was utilized by 36.4% of participants over the 12-month study period.
  • CAHC use was associated with poorer global health and physical functioning (p < 0.05).
  • No significant association was found between CAHC use and improved HRQOL, reduced pain, or decreased disease severity.
  • CAHC users demonstrated higher adherence to prescribed medications as assessed by rheumatologists.

Conclusions:

  • CAHC use in children with JIA does not lead to improved health outcomes in the short term.
  • Despite lack of outcome improvement, CAHC use is linked to enhanced adherence to conventional medical treatments in JIA patients.
  • Further research is needed to understand the complex interplay between CAHC, treatment adherence, and outcomes in pediatric rheumatic diseases.
Abstract

Related Concept Videos

Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents01:29

Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents

Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel Disease...
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids01:21

Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids

Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2 (COX-2),...
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...