Related Experiment Video
Updated: Jun 20, 2026
08:53
Label-free Single Molecule Detection Using Microtoroid Optical Resonators
Published on: December 29, 2015
Sensitive label-free and compact biosensor based on concentric silicon-on-insulator microring resonators
Xiaohui Li1, Ziyang Zhang, Shenying Qin
1Department of Electronic Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Applied Optics
|September 3, 2009
Summary
We developed a compact biosensor using concentric silicon microring resonators. This novel design offers enhanced sensitivity and a larger detection area for DNA hybridization detection.
Area of Science:
- Photonics
- Nanotechnology
- Biomedical Engineering
Background:
- Label-free biosensors are crucial for real-time biomolecular detection.
- Conventional microring resonator sensors face limitations in sensitivity and detection area.
- Silicon-on-insulator (SOI) platform offers advantages for integrated photonic devices.
Purpose of the Study:
- To propose and numerically analyze an ultracompact parallel label-free biosensor.
- To enhance sensitivity and detection area compared to single-ring resonators.
- To investigate DNA hybridization detection using concentric microring resonators.
Main Methods:
- Numerical simulations of concentric silicon-on-insulator microring resonators.
- Analysis of probe immobilization strategies (on-top and in-gap).
- Calculation of bulk detection sensitivity and analysis of optical field distribution.
Main Results:
- The proposed concentric double-ring resonator biosensor shows higher sensitivity.
- A bulk detection sensitivity of 683 nm RIU⁻¹ was achieved for a 27.646 µm² system.
- Analysis confirmed sensitive uniformity related to optical field distribution.
Conclusions:
- Ultracompact parallel label-free biosensors based on concentric microring resonators are feasible.
- The proposed design significantly improves upon conventional single-ring sensors.
- This technology holds promise for advanced DNA hybridization detection applications.
