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Updated: Jun 20, 2026

An Orthotopic Murine Model of Human Prostate Cancer Metastasis
06:48

An Orthotopic Murine Model of Human Prostate Cancer Metastasis

Published on: September 18, 2013

AsialoGM1 and integrin alpha2beta1 mediate prostate cancer progression

Severine Van Slambrouck1, John Hilkens, Marco Bisoffi

  • 1Department of Chemistry, Laboratory of Biochemical and Biomedical Research, New Mexico Tech, Socorro, NM 87801, USA. severine@nmt.edu

International Journal of Oncology
|September 3, 2009
PubMed
Summary

AsialoGM1 enhances prostate cancer metastasis by interacting with integrin alpha2beta1, promoting cell adhesion, migration, and invasion. This discovery offers new therapeutic targets for advanced cancer treatment.

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