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Updated: Jun 20, 2026

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Immunostaining-Based Detection of Dynamic Alterations in Red Blood Cell Proteins
Published on: March 17, 2023
Label-free imaging by stimulated parametric emission microscopy reveals a difference in hemoglobin distribution
Journal of Biomedical Optics
|September 4, 2009
Abstract:
We demonstrate that stimulated parametric emission (SPE) microscopy enables label-free, 3-D visualization of internal hemoglobin distribution of live mouse and chicken erythrocytes with high sensitivity. Change in hemoglobin distribution in chicken erythrocytes before and after ethanol fixation is clearly visualized.

