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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
[Spondylodiscitis: Diagnosis and medium-long term follow up of 18 cases]
R Tapia Moreno1, M G Espinosa Fernández, M I Martínez León
1Unidad de Reumatología Pediátrica, Hospital Materno-Infantil del Complejo Hospitalario Universitario Carlos Haya, Málaga, España. tapiarocio@yahoo.es
Insights
Pediatric spondylodiscitis is often misdiagnosed, leading to delayed treatment. Magnetic resonance imaging (MRI) is crucial for diagnosing this serious spinal infection and its complications in children.
Area of Science:
- Pediatric infectious diseases
- Spinal infections
- Pediatric radiology
Context:
- Spondylodiscitis is an uncommon but serious condition in children.
- Delayed diagnosis is frequent, potentially leading to complications.
- Clinical presentation varies significantly with age.
Purpose:
- To review the clinical, analytical, and radiological characteristics of pediatric spondylodiscitis.
- To identify diagnostic challenges and common presentations in children.
- To evaluate the role of imaging in diagnosis and management.
Summary:
- A retrospective study of 18 children with spondylodiscitis revealed diagnostic delays averaging 26.9 days, with initial misdiagnosis in 8 cases.
- Age-specific clinical patterns were observed, and magnetic resonance imaging (MRI) diagnosed 100% of cases, identifying complications like abscesses and nerve root damage.
- While most children recovered with antibiotics and immobilization, those with psoas abscesses had a prolonged recovery. MRI is essential for assessing disease extent.
Impact:
- Highlights the importance of early recognition and diagnosis of pediatric spondylodiscitis.
- Emphasizes the critical role of MRI in the accurate diagnosis and management of spinal infections in children.
- Provides insights into age-specific clinical manifestations to aid clinicians in prompt identification.
Introduction:
Spondylodiscitis is an uncommon disease in children. It is often misdiagnosed or the diagnosis is made late in the course of illness.
Objectives:
To review the clinical, analytical and radiological characteristics of children with spondylodiscitis in the Materno-Infantil Hospital of Malaga.
Patients And Methods:
Retrospective cohort study on children diagnosed with spondylodiscitis, during a period of 11 years.
Results:
Eighteen patients were included in the study. Spondylodiscitis was more frequent in patients younger than 3 years old and older than 12 years old. The average time of delay in diagnosis was 26.9 days. In 8 cases the diagnosis was missed initially. Three clinical patterns appeared: in children under 3 years of age, refusing to walk and sit (100%) and irritability (42%); between 3 and 12 years of age, limb (100%) and abdominal pain (100%); in adolescents, back pain (75%). Fever was present in 38% of the cases, and low-grade fever in 8 (44%). A total of 50% of the patients had a moderate leucocytosis, and a slight increase in ESR; the most frequent location was L3-L4. X-ray diagnosis was pathological in 88% of the cases. The initial MRI diagnosed 100% of the cases. In addition, nerve roots damage (5 cases), inflammatory masses/paravertebral abscesses (5), epidural abscess (1) and psoas abscesses (2) were detected. A total of 94% of the children received antibiotics and 100% of the children underwent immobilization. All patients recovered early after the beginning of treatment, with the exception of those affected by psoas abscesses. The radiological follow-up was done in 17 patients (12 by MRI). After a mean of 14 months (rank 1-48), persistent diminution of disc space was seen in 100% of the children, and improvement of soft-tissue inflammation. Clinically (follow-up only in 11 patients) all patients regained normal mobility and only 27% had moderate pain.
Conclusion:
Spondylodiscitis, whose delay in the diagnosis is frequent, is a serious illness. Complications include abscesses and nerve root damage. MRI is the study of choice to determine the extension to neighbouring tissues.
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