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Updated: Jun 20, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Lofgren syndrome: the relevance of the chest X-ray]
Catarina Ambrósio1, Armando Malcata
1Médica do Internato Complementar de Reumatologia dos Hospitais da Universidade de Coimbra, Praceta Mota Pinto, Coimbra. catambrosio1@netcabo.pt
Abstract:
Sarcoidosis is a systemic granulomatosis of unknown origin characterized by a formation of non-caseating granulomas in multiple organs, which can present as a chronic, sub acute or an acute form. Löfgren's syndrome is an acute form of sarcoidosis characterized by the presence of arthritis/arthralgia, eritema nodosum lesions and hilar lymphadenopathy. The authors present 3 case reports of arthritis/ /arthralgia and eritema nodosum lesions in 3 young patients in which the diagnosis was Löfgren's syndrome. The radiological findings were essential for the final diagnosis, especially in the presence of a normal value of serum angiotensin-converting enzyme.
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