Related Experiment Video
Updated: Jun 20, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
Assembly of unusual Zn-cluster compounds based on pyridinealcohol platforms
Daniele Anselmo1, Eduardo C Escudero-Adán, Jordi Benet-Buchholz
1Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007, Tarragona, Spain.
Abstract:
The assembly formation of Zn cluster compounds comprising pyridinealcohol ligands is described and their solution and solid state features have been determined using NMR spectroscopy and X-ray diffraction. The di-Zn complex 5 and tetra-Zn complex 7 may serve as accessible structural models for the active site of various multinuclear Zn-containing metalloenzymes. Their phosphoester cleavage activity was tested and correlated with their dynamic structural features.
More Related Videos
06:35Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates
Published on: February 15, 2016
07:14Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers
Published on: May 12, 2023
Related Concept Videos
Acid Halides to Esters: Alcoholysis
Diazonium Group Substitution: –OH and –H
Preparation of Alcohols via Substitution Reactions
Alcohols can be synthesized from alkyl halides via nucleophilic substitution reactions. The highly polar carbon-halogen bond in the substrate makes halide a good leaving group. The hydroxide ion or water can act as a nucleophile to take the place of halide and form an alcohol. The substitution reactions occur via two different reaction pathways, SN1 or SN2, depending on the nature of carbon attached to the halide.
Primary alcohols are synthesized from primary alkyl halides, and the...
Preparation of Alcohols via Addition Reactions
The acid-catalyzed addition of water to the double bond of alkenes is a large-scale industrial method used to synthesize low-molecular-weight alcohols. An acidic atmosphere is required to allow the hydrogen in the water molecule to act as an electrophile and attack the double bond in an alkene. The addition of a proton to the double bond creates a carbocation intermediate. The proton preferentially bonds to the less substituted end of the double bond to create a more stable carbocation...
Carboxylic Acids to Methylesters: Alkylation using Diazomethane
Diazonium Group Substitution with Halogens and Cyanide: Sandmeyer and Schiemann Reactions