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Published on: February 27, 2026
[Bilateral third cranial nerve palsy secondary to lung carcinoma metastasis]
J A Reche-Sainz1, S García-Sáenz, N Toledano-Fernández
1Servicio de Oftalmología, Hospital de Madrid Norte-Sanchinarro, Madrid, España. jalbres@yahoo.es
Clinical Case:
A 58 year-old man with a known diagnosis of a large cell lung carcinoma, developed a progressive diplopia. His examination revealed a double oculomotor nerve palsy with dilated and poorly reactive pupils. A cranial magnetic resonance showed an unique and solitary lesion in the midbrain, which presumably affected to both oculomotor nucleus and fasciculus. There were not found additional extrathoracic manifestations.
Discussion:
This case shows the possibility that a large cell lung carcinoma may cause a double oculomotor nerve palsy as the consequence of an isolated midbrain metastasis.
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