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Published on: August 1, 2013
[Excitatory amino acids, central nervous system neurotransmitters]
1Université Aix-Marseille II, Laboratoire de Neurosciences Fonctionnelles du CNRS, Marseille.
Abstract:
Excitatory amino acids play a crucial role in cerebral transmission. Numerous neuronal systems have been identified contributing to learning, memory and brain neuronal plasticity. Recent advances in neuropathology led to propose a crucial role of these neurotransmitters in neurodegenerative processes and acute cerebral strokes due to their excitotoxic properties. Consequently, development of excitatory amino acid antagonists constitutes a challenge for modern neuropharmacology.
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