[Excitatory amino acids, central nervous system neurotransmitters]

Excitatory amino acids play a crucial role in cerebral transmission. Numerous neuronal systems have been identified contributing to learning, memory and brain neuronal plasticity. Recent advances in neuropathology led to propose a crucial role of these neurotransmitters in neurodegenerative processes and acute cerebral strokes due to their excitotoxic properties. Consequently, development of excitatory amino acid antagonists constitutes a challenge for modern neuropharmacology.