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Behavioral and emotional problems in children with sickle cell disease and healthy siblings: Multiple informants,

Channa T Hijmans1, Martha A Grootenhuis, Jaap Oosterlaan

  • 1Psychosocial Department, Emma Children's Hospital, Academic Medical Center, Amsterdam, the Netherlands. c.t.hijmans@amc.uva.nl

Pediatric Blood & Cancer
|September 5, 2009
PubMed

Insights

Children with sickle cell disease (SCD) experience more internalizing behavioral and emotional problems than healthy peers. Some children with SCD also face externalizing issues, potentially linked to disease or socio-demographic factors.

Area of Science:

  • Pediatric Psychology
  • Hematology
  • Child Psychiatry

Background:

  • Sickle cell disease (SCD) is associated with potential behavioral and emotional challenges.
  • These issues may stem from disease-related factors or socio-demographic influences.
  • Understanding these problems is crucial for comprehensive care in children with SCD.

Purpose of the Study:

  • To determine the prevalence of behavioral and emotional problems in children with SCD.
  • To compare these problems in children with SCD to healthy siblings and a general population.
  • To identify potential contributing factors to these challenges.

Main Methods:

  • Utilized the Child Behavior Checklist (CBCL) and Teacher Report Form (TRF).
  • Included the Disruptive Behavior Disorders (DBD) rating scale for comprehensive assessment.
  • Collected data from caregivers and teachers of children with SCD and healthy siblings.

Main Results:

  • Children with SCD exhibited more internalizing problems than both healthy siblings and the norm population.
  • Teachers reported more externalizing problems in subgroups of children with SCD and healthy siblings compared to the norm.
  • Children with SCD showed greater school functioning difficulties, reduced social competence, and more attention deficits.

Conclusions:

  • Children with SCD are at higher risk for internalizing problems due to their condition.
  • Increased risk for severe externalizing problems in some children with SCD may be linked to socio-demographic factors or disease-related neurocognitive deficits, such as cerebral infarction.
Abstract

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