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Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

Pulmonary Tuberculosis II

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

Pulmonary Tuberculosis III

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

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Related Experiment Video

Updated: Jun 20, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

[Primary pulmonary sarcomas].

T Jakubcová¹, P Jakubec

¹Klinika plicních nemocí a tuberkulózy FN a LF UP, Olomouc. tereza.jakubcova@fnol.cz

Klinicka Onkologie : Casopis Ceske a Slovenske Onkologicke Spolecnosti

|September 8, 2009

Summary

Primary pulmonary sarcomas are rare malignant mesenchymal tumors originating in the lung. Diagnosis requires biopsy, and optimal treatment involves surgical resection, though outcomes remain challenging.

Area of Science:

Oncology
Pathology
Medical Research

Context:

Primary pulmonary sarcomas are rare malignant mesenchymal tumors, distinct from lung carcinomas.
They originate from soft tissues within the lung and exhibit diverse biological behaviors.
Unlike lung carcinomas, they predominantly affect children and young adults.

Purpose:

To review the characteristics, diagnosis, treatment, and prognosis of primary pulmonary sarcomas.
To highlight diagnostic challenges, particularly differentiating primary from secondary sarcomas in the lung.
To discuss current therapeutic modalities and emerging biological treatments.

Summary:

Primary pulmonary sarcomas are rare, aggressive mesenchymal tumors of the lung, often occurring in younger individuals.

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Last Updated: Jun 20, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

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Published on: April 21, 2022

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

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Published on: February 27, 2026

Diagnosis relies on biopsy with histologic and immunohistochemistry examination, crucial for excluding metastatic disease.

Optimal treatment is surgical resection, with radiotherapy and chemotherapy showing limited efficacy; biological therapies are under investigation.

Impact:

Improved understanding of primary pulmonary sarcomas aids in accurate diagnosis and management strategies.
Highlights the need for further research into effective treatments beyond surgery, radiotherapy, and chemotherapy.
Emphasizes the poor prognosis associated with these rare tumors, underscoring the importance of early detection and novel therapeutic approaches.