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Related Experiment Video

Updated: Jun 20, 2026

Radiosynthesis of 1-(2-[18F]Fluoroethyl)-L-Tryptophan using a One-pot, Two-step Protocol

Radiosynthesis of 1-(2-[¹⁸F]Fluoroethyl)-L-Tryptophan using a One-pot, Two-step Protocol

Published on: September 21, 2021

Triptans: low utilization and high turnover in the general population.

A Panconesi¹, E Pavone, M Franchini

¹Health Authority 11, Empoli, Florence, Italy. a.panconesi@virgilio.it

Cephalalgia : an International Journal of Headache

|September 8, 2009

Summary

Triptan utilization for migraine is low, with frequent discontinuation and new users, suggesting poor patient satisfaction with this treatment. This indicates a high turnover in triptan therapy.

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Last Updated: Jun 20, 2026

Radiosynthesis of 1-(2-[18F]Fluoroethyl)-L-Tryptophan using a One-pot, Two-step Protocol

Radiosynthesis of 1-(2-[¹⁸F]Fluoroethyl)-L-Tryptophan using a One-pot, Two-step Protocol

Published on: September 21, 2021

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Area of Science:

Neurology
Pharmacology
Public Health

Background:

Previous studies indicated suboptimal triptan use in specific populations.
Understanding triptan utilization patterns in a broad community is essential for improving migraine management.

Purpose of the Study:

To analyze triptan utilization trends in a large Italian community over two years.
To identify patterns of prescription, discontinuation, and new use of triptans.

Main Methods:

Utilized pharmaceutical prescription data from a regional Health Authority in Italy.
Analyzed prescription data for two consecutive years to track triptan use.

Main Results:

Approximately 0.5% of the population received triptan prescriptions annually.
Over 50% received only one prescription, and 46% of users did not receive a prescription the following year.
A high turnover was observed, with 52% of users being new in the second year and less than 15% receiving multiple triptan products over two years.

Conclusions:

Triptan therapy exhibits low utilization rates, high discontinuation, and significant user turnover.
These patterns suggest potential dissatisfaction with triptan treatment and suboptimal migraine management.
Further research is needed to address barriers to consistent and effective triptan use.