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Updated: Jun 20, 2026

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
Published on: February 24, 2023
Adult community-acquired pneumonia caused by macrolide resistant Mycoplasma pneumoniae
Rie Isozumi1, Hiroyuki Yoshimine, Miyuki Morozumi
1Inoue Hospital, Nagasaki 850-0045, Japan. wushiqilihui@hotmail.co.jp
Abstract:
A 28-year-old woman with community-acquired pneumonia was treated with sulbactam/ampicillin and clarithromycin, but failed to show any improvement after 4 days. The antibiotic regimen was changed to pazufloxacin and rapid clinical improvement was seen. Mycoplasma pneumoniae was identified as the causative agent, and adenine (A) to guanine (G) mutation at position 2063 in domain V of the 23S rRNA was noted in the isolate. The minimum inhibitory concentration of macrolide antibiotics, including clarithromycin, of this isolate was greatly elevated.
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