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Evaluation of a single-step diagnosis and treatment of premalignant cervical lesion by LEEP
Mohamed Emam1, Aboubakr Elnashar, Hesham Shalan
1Mansura University Hospital, Mansura, Egypt.
Objective:
To explore whether a single-step diagnosis and treatment of premalignant cervical lesions by the loop electrosurgical excision procedure (LEEP) is appropriate in women at high risk in low-resource countries.
Method:
Sixty women suspected of having a high-grade lesion on both visual inspection with acetic acid (VIA) and colposcopic examination were randomly allotted to one of 2 groups. In group 1, LEEP was performed immediately and a tissue specimen was sent for histopathologic evaluation; in group 2, a punch biopsy was performed, followed by a histopathologic evaluation; then, LEEP was performed if needed.
Results:
Among the patients who underwent LEEP, 4 (16%) in group 1 and 3 (15.8%) in group 2 were overtreated. No patients dropped out of the study in group 1 but 5 (20.8%) did in group 2.
Conclusion:
The single-step diagnosis and LEEP treatment of premalignant cervical lesions is appropriate in low-resource countries.