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Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
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Increased activation in cingulate cortex in conversion disorder: what does it mean?

M van Beilen1, B A Vogt, K L Leenders

  • 1Department of Neurology, University Medical Center Groningen, University of Groningen, The Netherlands. m.van.beilen@neuro.umcg.nl

Journal of the Neurological Sciences
|September 8, 2009
PubMed
Summary
This summary is machine-generated.

Conversion disorder involves psychosomatic neurological symptoms from psychological conflict. Neuroimaging shows increased anterior cingulate gyrus activation, but its role in conversion disorder remains unclear, prompting a neuroanatomical review.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Psychosomatic Medicine

Background:

  • Conversion disorder presents as psychosomatic neurological symptoms potentially stemming from psychological conflict.
  • Identifiable psychological stressors are often present, comparable in severity to those in non-psychosomatic neurological disorders.
  • Neuroimaging studies consistently report heightened anterior cingulate gyrus activation in conversion disorder.

Purpose of the Study:

  • To re-examine current theories of conversion disorder.
  • To analyze these theories from a neuroanatomical perspective.
  • To clarify the functional significance of anterior cingulate gyrus activation in conversion disorder.

Main Methods:

  • Review of existing literature on conversion disorder.
  • Analysis of neuroimaging findings, particularly in the anterior cingulate gyrus.
  • Theoretical re-evaluation based on neuroanatomical evidence.

Main Results:

  • Anterior cingulate gyrus activation is a consistent finding in conversion disorder.
  • This activation is theorized to reflect 'active inhibition' or 'self-monitoring'.
  • The precise neuroanatomical meaning of this activation in conversion disorder remains debated.

Conclusions:

  • Current theories on conversion disorder require re-examination through a neuroanatomical lens.
  • Further research is needed to elucidate the role of the anterior cingulate gyrus in the pathophysiology of conversion disorder.
  • Understanding the neuroanatomy may provide insights into the mechanisms underlying psychosomatic symptoms.