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Updated: Jun 20, 2026

T Cells Capture Bacteria by Transinfection from Dendritic Cells
Published on: January 13, 2016
B-cells get the T-cells but antibodies get the worms
Richard J Pleass1, Jerzy M Behnke
1Institute of Genetics, and Parasite Biology and Immunogenetics Research Group, Queen's Medical Centre, University of Nottingham, NG7 2UH, UK. richard.pleass@nottingham.ac.uk
Abstract:
Two recent papers published in Immunity and Cell Host & Microbe underline the great importance of B cells and of antibodies (Abs) in orchestrating crucial T helper cell type 2 (Th2) protective immune responses to gastrointestinal nematodes. The findings in animal models now raise major questions as to how B cells and Abs carry out these functions in humans. Here we discuss recent technological advances in humanizing animal models at the level of both Abs and their Fc-receptors, that might provide some answers.
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