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Related Experiment Video

Updated: Jun 20, 2026

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

Published on: October 10, 2019

Risk factors for exercise-related acute cardiac events. A case-control study.

W M van Teeffelen¹, M F de Beus, A Mosterd

¹Department of Sports Medicine, Canisius Welhelmina Ziekenhuis, Nijmegen, The Netherlands.

British Journal of Sports Medicine

|September 8, 2009

Summary

Exercise can trigger cardiac events in athletes with underlying risks. Prior cardiovascular disease, smoking, recent fatigue, or flu-like symptoms significantly increase this risk, highlighting the need for awareness and prevention strategies.

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Last Updated: Jun 20, 2026

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

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Published on: October 10, 2019

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Published on: May 5, 2022

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

Area of Science:

Sports Medicine
Cardiology
Exercise Physiology

Background:

Physical activity offers numerous health benefits but can precipitate acute cardiac events in predisposed individuals.
Identifying risk factors for exercise-related acute cardiac events is crucial for developing preventive measures.

Purpose of the Study:

To investigate the determinants of acute cardiac events occurring during or shortly after vigorous exercise in athletes.

Main Methods:

A case-control study design was employed.
Cases comprised athletes experiencing acute cardiac events during/after exercise; controls were athletes with minor sports injuries.
Data on cardiovascular disease history, family history, symptoms, and other risk factors were collected via questionnaires.

Main Results:

The study included 57 cases and 57 controls.
A history of cardiovascular disease was strongly associated with exercise-related cardiac events (Odds Ratio [OR] = 32).
Smoking (OR = 5.9), recent fatigue (OR = 12), and flu-like symptoms (OR = 13) were also linked to increased risk.

Conclusions:

Pre-existing cardiovascular disease, smoking, and recent illness (fatigue or flu-like symptoms) are significant risk factors for exercise-related acute cardiac events.
Athletes and healthcare providers should exercise caution when these risk factors are present.