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Heterotopic pancreatic tissue obstructing the gallbladder neck: a case report
Justin L Weppner1, Matthew R Wilson, Robert Ricca
1United States Navy, General Surgery Department, Portsmouth Naval Medical Center, Portsmouth, VA 23708-2197, USA. cdvfdrs@gmail.com
JOP : Journal of the Pancreas
|September 8, 2009
Summary
Heterotopic pancreatic tissue, pancreatic tissue outside the pancreas, can cause gallbladder issues. A rare case involved this tissue obstructing the gallbladder neck, leading to acute cholecystitis in a young woman.
Area of Science:
- Gastroenterology
- Pathology
Background:
- Heterotopic pancreatic tissue (HPT) is pancreatic tissue found outside the pancreas without anatomical or vascular connection.
- HPT within the gallbladder is rare and infrequently symptomatic.
Observation:
- A 26-year-old female presented with symptoms of acute cholecystitis, including right upper quadrant pain and fever.
- Imaging revealed gallbladder wall thickening and an apparent stone at the gallbladder neck.
- Pathology confirmed acute cholecystitis caused by a necrotic mass of heterotopic pancreatic tissue obstructing the gallbladder neck.
Findings:
- Microscopic examination identified exocrine pancreatic acini, ducts, and islets of Langerhans within the obstructing mass.
- The final diagnosis was acute cholecystitis secondary to obstruction by heterotopic pancreatic tissue.
Implications:
- Heterotopic pancreatic tissue should be considered in the differential diagnosis of gallbladder diseases with unclear causes.
- This case highlights a rare but significant cause of symptomatic gallbladder pathology.
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