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Related Concept Videos

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...

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Related Experiment Video

Updated: Jun 20, 2026

Folding and Characterization of a Bio-responsive Robot from DNA Origami
07:59

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

DNA nanotechnology: Geometric sorting boards.

David W Grainger

    Nature Nanotechnology
    |September 8, 2009
    PubMed
    Summary
    This summary is machine-generated.

    DNA origami tiles precisely bind to complementary patterned surfaces. This DNA self-assembly method enables nanoscale surface patterning for advanced applications.

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    Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
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    Last Updated: Jun 20, 2026

    Folding and Characterization of a Bio-responsive Robot from DNA Origami
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    DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
    08:59

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    Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
    10:23

    Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles

    Published on: May 8, 2015

    Area of Science:

    • Nanotechnology
    • Biomolecular Engineering
    • Surface Science

    Background:

    • DNA origami enables the programmable self-assembly of nanoscale structures.
    • Lithographically patterned surfaces offer precise spatial control for molecular organization.

    Discussion:

    • This study demonstrates the specific binding of DNA origami tiles to shape-complementary sites on patterned surfaces.
    • The interaction relies on the precise geometric matching between DNA structures and surface features.

    Key Insights:

    • DNA origami tiles can be directed to specific locations on surfaces via shape complementarity.
    • This provides a method for high-resolution, DNA-based surface patterning.

    Outlook:

    • Potential applications in nanoscale device fabrication, biosensing, and self-assembling materials.
    • Further research could explore dynamic patterning and integration with other nanoscale components.